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Listar por autor "Hmadcha, Abdelkrim"
Mostrando ítems 1-20 de 23
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Artículo
Derivation of HVR1, HVR2 and HVR3 human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis (PGD) for monogenic disorder
Hmadcha, Abdelkrim; Aguilera, Yolanda; Lozano Arana, María Dolores; Mellado, Nuria; Sánchez, Javier; Moya, Cristina; Sánchez Palazón, Luis; Palacios Calvo, José; Antiñolo Gil, Guillermo; Soria Escoms, Bernat (Elsevier, 2016)From 106 human blastocyts donate for research after in vitro fertilization (IVF) and preimplantation genetic diagnosis (PGD) ...
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Editorial: A Compendium of Recent Research on Stem Cell-Based Therapy for Covid-19
Hmadcha, Abdelkrim; Soria, Bernat; Zhao, Robert C.; Smani Hajami, Tarik; Valverde Pérez, Israel (Frontiers Media, 2021-12-14)We have been dealing with an unprecedented global health crisis for nearly 2 years now. This started after an outbreak of ...
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Artículo
EGF-induced adipose tissue mesothelial cells undergo functional vascular smooth muscle differentiation
Lachaud, Christian; López Beas, Javier; Soria Escoms, Bernat; Hmadcha, Abdelkrim (Nature Publishing Group, 2014)Recent studies suggested that the post-natal mesothelium retain differentiative potential of the embryonic mesothelium, ...
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Tesis Doctoral
Epigenética de los procesos de autorrenovación, pluripotencialidad y diferenciación de las células troncales
Horrillo Ledesma, Angélica (2010)El objetivo general de esta tesis ha sido definir la importancia que poseen los procesos epigenéticos sobre el mantenimiento ...
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Tesis Doctoral
Expresión del gen FMR1 y su represión por Óxido Nítrico vía metilación del promotor
Hmadcha, Abdelkrim (2000) -
Artículo
Fragile X founder effect and distribution of CGG repeats among the mentally retarded population of Andalusia, South Spain
Carrasco, Mercedes; Diego Otero, Yolanda de; Morón Civanto, Francisco Jesús; Pintado Sanjuán, Elizabeth; Lucas Lucas, Miguel; Hmadcha, Abdelkrim; Morón, F. (2002) -
Artículo
Human Mesenchymal Stem Cells Prevent Neurological Complications of Radiotherapy
Soria Escoms, Bernat; Martín Montalvo, Alejandro; Aguilera García, Yolanda; Mellado, Nuria; López Beas, Javier; Herrera-Herrera, Isabel; López, Escarlata; Barcia, Juan A.; Álvarez Dolado, Manuel; Hmadcha, Abdelkrim; Capilla González, Vivian (Frontiers Media S.A., 2019-05-16)Radiotherapy is a highly effective tool for the treatment of brain cancer. However, radiation also causes detrimental ...
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Human Omental Mesothelial Cells Impart an Immunomodulatory Landscape Impeding B- and T-Cell Activation
Gauthier, Benoit R.; Rubio Contreras, Diana; Gómez Rosado, Juan Carlos; Capitán Morales, Luis Cristobal; Hmadcha, Abdelkrim; Soria, Bernat; Lachaud, Christian Claude (MDPI, 2022)Mesothelial cells form the mesothelium, a simple epithelium lining the walls of serous cavities and the surface of visceral ...
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Impact of transient down-regulation of DREAM in human embryonic stem cell pluripotency: The role of DREAM in the maintenance of hESCs
Fontán Lozano, Ángela del Carmen; Capilla González, Vivian; Aguilera, Yolanda; Mellado, Nuria; Carrión Rodríguez, Ángel Manuel; Soria Escoms, Bernat; Hmadcha, Abdelkrim (Elsevier, 2016)Little is knownabout the functions of downstreamregulatory element antagonist modulator (DREAM) inembryonic stem cells ...
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Artículo
Low concentrations of nitric oxide delay the differentiation of embryonic stem cells and promote their survival
Martín, F.; Tejedo Huamán, Juan Rigoberto; Tapia Limonchi, R.; Mora Castilla, S.; Hmadcha, Abdelkrim; Soria Escoms, Bernat; Bedoya Bergua, Francisco Javier; Cahuana Macedo, Gladys Margot (2010) -
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LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus
Cobo Vuilleumier, Nadia; Lorenzo, Petra I.; García Rodríguez, Noelia; Herrera Gómez, Irene G.; Fuente Martín, Esther; López Noriega, Livia; Mellado Gil, José Manuel; Romero Zerbo, Silvana Y.; Lachaud, Christian; Hmadcha, Abdelkrim; Sánchez Palazón, Luis; Martín Montalvo, Alejandro; Soria Escoms, Bernat; Gauthier, Benoit R. (Nature Publishing Group, 2018-04-16)Type 1 diabetes mellitus (T1DM) is due to the selective destruction of islet beta cells by immune cells. Current therapies ...
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Tesis Doctoral
Medicamento celular como alternativa terapéuticaen la isquemiacrónica crítica de miembros inferiores en pacientes diabéticos sin posibilidades de revascularización
Escacena Acosta, Natalia (2016-02-11)La diabetes mellitus (DM) es la enfermedad metabólica más común, y comprende una variedad de síndromes con distintas causas ...
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Artículo
Methylation-dependent gene silencing induced by interleukin 1β via nitric oxide production
Hmadcha, Abdelkrim; Bedoya Bergua, Francisco Javier; Sobrino, Francisco; Pintado Sanjuán, Elizabeth (Rockefeller University Press, 1999-12-06)Interleukin (IL)-1 b is a pleiotropic cytokine implicated in a variety of activities, including damage of insulin-producing ...
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miR-7 Modulates hESC Differentiation into Insulin-Producing Beta-like Cells and Contributes to Cell Maturation
López Beas, Javier; Capilla González, Vivian; Aguilera, Yolanda; Mellado, Nuria; Lachaud, Christian; Martín, Franz; Smani Hajami, Tarik; Soria Escoms, Bernat; Hmadcha, Abdelkrim (The American Society of Gene and Cell Therapy, 2018-09-07)Human pluripotent stem cells retain the extraordinary capacity to differentiate into pancreatic beta cells. For this ...
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Artículo
Oestrogen receptor β mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells
Martínez-Pinna, Juan; Marroquí, Laura; Hmadcha, Abdelkrim; López Beas, Javier; Soriano, Sergi; Villar-Pazos, Sabrina; Alonso-Magdalena, Paloma; Santos, Reinaldo; Quesada, Iván; Martin, Franz; Soria Escoms, Bernat (Springer Nature, 2019-09)Aims/hypothesis: Bisphenol-A (BPA) is a widespread endocrine-disrupting chemical that has been associated with type 2 ...
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Artículo
Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation
Roodveldt, Cintia; Labrador Garrido, Adahir; González Rey, Elena; Lachaud, Christian; Guilliams, Tim; Fernández Montesinos, Rafael; Benítez Rondan, Alicia; Robledo, Gema; Hmadcha, Abdelkrim; Delgado, Mario; Dobson, Christopher M.; Pozo, D. (PLOS, 2013)In recent years, it has become accepted that α-synuclein (αSyn) has a key role in the microglia-mediated neuroinflammation, ...
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Artículo
Resveratrol Ameliorates the Maturation Process of β-Cell-Like Cells Obtained from an Optimized Differentiation Protocol of Human Embryonic Stem Cells
Pezzolla, Daniela; López Beas, Javier; Lachaud, Christian; Domínguez Rodríguez, Alejandro; Smani Hajami, Tarik; Hmadcha, Abdelkrim (Public Library of Science, 2015)Human embryonic stem cells (hESCs) retain the extraordinary capacity to differentiate into different cell types of an adult ...
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Artículo
The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity article
Mellado Gil, José Manuel; Fuente Martín, Esther; Lorenzo Ovejero, Petra Isabel; Cobo Vuilleumier, Nadia; López Noriega, Livia; Martín Montalvo, Alejandro; Gracia Herrera Gómez, Irene de; Ceballos Chávez, María; Romero Zerbo, Silvana Y.; Hmadcha, Abdelkrim; Soria Escoms, Bernat; Bermúdez Silva, Francisco Javier; Reyes, José C.; Gauthier, Benoit R. (Springer Nature [academic journals on nature.com, 2018)HMG20A (also known as iBRAF) is a chromatin factor involved in neuronal differentiation and maturation. Recently small ...
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Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy
Hmadcha, Abdelkrim; Martín Montalvo, Alejandro; Gauthier, Benoit R.; Soria Escoms, Bernat; Capilla González, Vivian (Frontiers Media S.A., 2020)Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine. A large number of ...
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Artículo
Tissue engineered in-vitro vascular patch fabrication using hybrid 3D printing and electrospinning
Mayoral González, Isabel; Bevilacqua, Elisa; Gómez, Gorka; Hmadcha, Abdelkrim; González-Loscertales, Ignacio; Reina Romo, Esther; Sotelo, Julio; Domínguez, Antonia; Pérez Alcántara, Pedro; Smani, Younes; González Puertas, Patricia Isabel; Méndez, Ana; Uribe, Sergio; Smani Hajami, Tarik; Ordóñez, Antonio; Valverde Pérez, Israel (Elsevier, 2022-03)Three-dimensional (3D) engineered cardiovascular tissues have shown great promise to replace damaged structures. Specifically, ...